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7.1 Iron chelators 7.1.1 Preclinical stage Natural and synthetic iron chelators in preclinical development exhibit neuroprotective potential by modulating cerebral iron dyshomeostasis, though their translational value requires further validation

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ROS are partially reduced derivatives of molecular oxygen and mainly divided into two groups: highly unstable oxygen free radicals such as superoxide anion radicals (O 2 ) and chemically stable nonradical oxidants such as hydrogen peroxide (H 2 O 2 ) [2]

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PMID: 15452611